Gene description for PAICS
Gene name	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
Gene symbol	PAICS
Other names/aliases	ADE2 ADE2H1 AIRC PAICSD PAIS
Species	Homo sapiens
Experiment description of studies that identified PAICS in Liver cancer cells
1 Experiment ID 2476 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM Mass spectrometry EV-TRACK -
2 Experiment ID 2477 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM Mass spectrometry EV-TRACK -